Taking melatonin by mouth doesn't improve behavior or affect symptoms in people with Alzheimer disease or other forms of memory loss. Diseases, such as Alzheimer disease, that interfere with thinking (dementia).Taking melatonin by mouth doesn't improve appetite, body weight, or body composition in people with wasting syndrome from cancer. Involuntary weight loss in people who are very ill (cachexia or wasting syndrome).Taking melatonin by mouth shortly before resistance exercise or cycling doesn't appear to improve performance. Taking melatonin by mouth can improve low blood platelet counts associated with cancer, cancer treatment, and other disorders.
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